Evaluation of Anti-Depressant Potential of Medicinal Ghrita

This article aims to evaluate the possible antidepressant effect of Ghrita prepared from combination these plants and provide probable scientific explanations for using medicated (ghee) in Ayurvedic system medicine. Herbs like Marsilea quadrifolia, Lawsonia inermis, Mimosa pudica, Piper betle were collected freshly during month June. One part Kalka (herb bolus), 4 parts pure cow ghee, 16 Dravadravya used make (Swarasa). Anti-depressant potential was evaluated by forced swimming, tail suspension, locomotor activity, rota-rod test (motor co-ordination), elevated plus maze (EPM) model, hole board assess Ghrita's anti-depressant potential. According Irwin schedule, Gritha medication reduces alertness but has no on other parameters, imipramine treatment responsiveness, alertness, grooming, writing reflexes some extent. Following 14 days therapy with medicinal Ghrita, immobility time swim suspension reduced 29% 42%, respectively. In rotarod test, it had significant muscle gripping ability when compared control animals, whereas produced a result. It observed that significantly (p<0.05) decreases activity actophotometer head dips counts as at end study 5 minute observation. increased number entries 50% spent open arm 72%. The results this investigation suggest Ghrita.